在炎症性角膜疾病病理过程中，细胞粘附分子和白细胞趋化因子在多形核白细胞的粘附、渗出和定向聚集这一系列关键环节中起十分重要的促进作用。ＮＦ－κＢ作为它们的转录调控因子，参与炎症的发生发展。本文简要介绍了核转录因子ＮＦ－κＢ的结构组成、激活途径、功能及检测方法，初步探讨了其在角膜炎症进程中可能的调控作用 In the pathological process of inflammatory corneal disease, cell adhesion molecules and leukocyte chemokines play a very important role in the adhesion, exudation and directional aggregation of polymorphonuclear leukocytes. NF-κB as their transcriptional regulator, involved in the occurrence and development of inflammation. This article briefly introduced the nuclear transcription factor NF-κB structural composition, activation pathway, function and detection methods, preliminary study of its possible regulation in the process of corneal inflammation