产毒的顽固性梭状芽孢杆菌是应用抗生素后并发结肠炎的主要原因。本文报道对16例顽固性梭状芽孢杆菌结肠炎或腹泻,应用口服两种不同剂量的万古霉素治疗的疗效。本组病人用抗生素或细胞毒素药4周内出现腹泻,每天5次或5次以上,且粪便中可检出顽固性梭状芽孢杆菌毒素。12例结肠炎经结肠活检、乙结肠镜 Staphylococcus aureus is a major cause of colitis associated with antibiotics. This article reports 16 cases of intractable Clostridium colitis or diarrhea, the application of oral administration of two different doses of vancomycin treatment. This group of patients with antibiotics or cytotoxic drugs within 4 weeks of diarrhea, 5 times a day or more, and can be found in stool stool Clostridium toxin. 12 cases of colitis by colon biopsy, B colonoscopy