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目的：通过ＳＤ大鼠肝癌模型的ＭＲＩ征象与病理对照研究，进一步验证人类肝癌的ＭＲＩ征象的病理基础。材料和方法：经腹腔种植Ｗａｌｋｅｒ－２５６癌肉瘤成功地建立ＳＤ大鼠肝癌模型２２只，共２８个病灶。使用１．５超导ＭＲ机扫描，观察ＭＲＩ图像，留取肿瘤标本行光镜及电镜观察，病理结果与ＭＲＩ征象对比，并与人类肝癌的ＭＲＩ征象和病理改变相对照。结果：ＳＤ大鼠肝癌模型的ＭＲＩ表现及病理改变与人类肝癌相似。结论：ＳＤ大鼠移植型肝癌模型是一种容易复制、实验周期短的肝癌模型，可作为人类肝癌影像研究的理想的动物模型
OBJECTIVE: To study the pathological basis of MRI features of human hepatocellular carcinoma by MRI features and pathological study of SD rat liver cancer model. Materials and Methods: Twenty-two SD rat liver cancer models were successfully established by implanting Walker-256 carcinosarcoma intraperitoneally. There were a total of 28 lesions. 1.5 ultrasound superconducting MR scans were used to observe the MRI images. The tumor specimens were observed under light and electron microscope. The pathological findings were compared with the MRI features and compared with the MRI features and pathological changes of human liver cancer. Results: The MRI findings and pathological changes of SD rat liver cancer model were similar to those of human liver cancer. Conclusion: The transplanted liver cancer model of SD rat is a liver cancer model that is easy to replicate and has a short experimental period. It can be used as an ideal animal model for the study of human liver cancer imaging.