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随着中草药在临床的广泛应用,有关其毒副作用和不良反应的报道日益增多。目前,中药复方煎剂导致肝损害的研究报道较少,治疗剂量所致的亚急性肝坏死实属罕见。 患者女性,63岁,2002年7月10日在我院诊断为“湿疹”,给予中药二妙散为主的复方煎剂治疗,服药20天后自觉周身乏力、上腹不适、腹胀、食欲不振、厌油腻、恶心、皮肤巩膜黄染、尿色加深呈豆油色、发热,体温37.8℃,停药。3天后来院于传染科
With the extensive application of Chinese herbal medicine in clinical practice, there are increasing reports about its side effects and adverse reactions. At present, there are few reports about the research on the liver damage caused by the traditional Chinese medicine compound decoction. Subacute hepatic necrosis caused by the therapeutic dose is rare. Female patient, 63 years old, diagnosed as “eczema” in our hospital on July 10, 2002. The compound decoction was given to the Chinese medicine Er Miao San. After 20 days of taking the medicine, he felt unconsciousness, abdominal distension, loss of appetite, Tired of greasy, nausea, skin sclera yellow dye, dark brown was soybean oil color, fever, body temperature 37.8 ℃, withdrawal. 3 days later came to the Department of Infectious Diseases