论文部分内容阅读
目的:探讨Ⅱ型糖尿病人游离胰岛素改变及与胰岛素、C肽关系。方法:样品预处理后用放免法测定34例Ⅱ型糖尿病游离胰岛素,同时测胰岛素抗体,与胰岛素、C肽作比较。结果:该组糖尿病人游离胰岛素各时相水平明显低于胰岛素(P<0.05),去除胰岛素抗体阳性者后,二者再比较,游离胰岛素仍低于胰岛素(P<0.05),游离胰岛素与胰岛素比较,峰值一致,游离胰岛素2h与C肽相应时相近相关(r=0.33,P=0.06)。结论:Ⅱ型糖尿病人正常胰岛素水平或高胰岛素血症者,其血中活性胰岛素并不增高
Objective: To investigate the change of free insulin and its relationship with insulin and C peptide in type 2 diabetes mellitus. Methods: After pretreatment, free insulin was measured in 34 patients with type Ⅱ diabetes mellitus by radioimmunoassay. At the same time, insulin antibody was measured and compared with insulin and C peptide. Results: The level of free insulin in each group was significantly lower than that of insulin at the same time (P <0.05). After removing insulin antibodies, the free insulin was still lower than that of insulin (P <0.05) Free insulin and insulin, the peak of the same, free insulin 2h and C peptide are closely related (r = 0.33, P = 0.06). Conclusion: Type 2 diabetes patients with normal insulin levels or hyperinsulinemia, the blood of active insulin is not increased