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报道1例海洛因海绵状白质脑病的临床和影像学,并综合文献进行分析。海洛因海绵状白质脑病具有如下特点:有经鼻烫吸海洛因史,急性或亚急性起病,多以小脑受损为首发症状,亦可表现为突然昏迷、抽搐、以运动障碍为主,脑脊液正常,影像学具有特征性的脑白质广泛受累,小脑白质受累最早,最严重。病变双侧对称,CT呈低密度,无占位效应.增强无强化。主要病理改变为脑白质海绵状变性,病因和发病机制目前尚不清楚,可能与海洛因不纯含有杂质等有关;对有海洛因烫吸史者,一旦出现脑部症状.要及早行影像学检查,明确诊断,对预防和治疗戒毒所引起的并发症具有指导意义。
Reported a case of heroin cavernous leukoencephalopathy clinical and imaging, and comprehensive literature analysis. Heroin spongiform encephalopathy has the following characteristics: nasal hot heroin history, acute or subacute onset, mostly cerebellar damage as the first symptom, can also be manifested as sudden coma, convulsions, dyskinesia, normal cerebrospinal fluid , Imaging features a broad spectrum of white matter involvement, cerebellar white matter involvement the earliest and most serious. Lesions bilateral symmetry, CT was low density, no mass effect. Enhance without enhancement. The main pathological changes of white matter spongiform degeneration, the etiology and pathogenesis is not yet clear, may be related to heroin impure impurities, etc. For those who have history of heroin burning, once the brain symptoms occur, A clear diagnosis, to prevent and treat the complications caused by drug treatment has guiding significance.