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目的:探讨保留肾单位手术治疗T_1期肾癌的临床疗效。方法:回顾性分析98例行保留肾单位手术治疗T_1期肾癌患者的临床资料,其中男66例,女32例,平均年龄51岁(41～65岁);对侧肾脏正常的患者85例,对侧肾脏存在疾患的患者13例;肿瘤平均直径2.4 cm(1.3～6.5 cm);病理分期均为T_1N_0M_0期;98例中93例行肾部分切除术,5例行肿瘤切除术。术后观察是否出现局部肾创面出血、漏尿等并发症,每3个月行腹部CT、肾脏ECT、超声及尿常规、肾功能检查。结果:98例手术均顺利完成,术后继发性出血3例、漏尿5例。随访10～12个月,平均10.3个月,2例术后6个月局部复发行根治性手术,其余96例无局部复发,无一例出现远处转移。结论:保留肾单位手术是治疗T_1期肾癌安全有效的方法,值得推广。
Objective: To investigate the clinical efficacy of nephron sparing surgery in the treatment of T_1 renal cell carcinoma. Methods: A retrospective analysis of 98 cases of renal cell surgery in patients with T_1 renal cell carcinoma of the clinical data, including 66 males and 32 females, mean age 51 years (41 to 65 years); contralateral normal kidney patients 85 cases , 13 cases of contralateral kidney disease patients; average diameter of 2.4 cm (1.3 ~ 6.5 cm); pathological staging were T_1N_0M_0; 98 cases of 93 cases of partial nephrectomy, 5 cases of tumor resection. Postoperative observation of local renal wound bleeding, leakage of urine and other complications every 3 months underwent abdominal CT, renal ECT, ultrasound and urine routine, renal function tests. Results: All the 98 surgeries were completed successfully. There were 3 cases of postoperative secondary hemorrhage and 5 cases of leakage of urine. The patients were followed up for 10 to 12 months with an average of 10.3 months. Two patients underwent radical operation with local recurrence 6 months after operation. The remaining 96 patients had no local recurrence and no distant metastasis occurred. Conclusion: The preservation of nephron surgery is a safe and effective method for the treatment of T_1 renal cell carcinoma and is worth promoting.