论文部分内容阅读
目的:观察3%高渗盐水联合肾上腺素雾化吸入治疗婴儿气管插管导致的喉头水肿疗效。方法:选择2010年1月~2013年5月本院进行机械通气的拔管后出现喉头水肿症状的婴儿60例。随机分为对照组与治疗组各30例。治疗组用肾上腺素溶于3%高渗盐水进行雾化吸入治疗,对照组用地塞米松溶于0.9%生理盐水中雾化吸入治疗。比较2组患儿喉头水肿症状持续时间、呼吸频率和心率。结果:治疗组喉头水肿持续时间为20.10±7.14小时,对照组为27.70±4.89小时,2组差异有统计学意义(P<0.05)。雾化吸入后第1个小时治疗组呼吸频率为35.86±7.92次/min,对照组为40.40±8.70次/min,治疗组呼吸频率较对照组低,2组差异有统计学意义(P<0.05);治疗组心率为146.93±9.67次/min,对照组为143.03±11.73次/min,2组差异无统计学意义(P>0.05)。结论:3%高渗盐水联合肾上腺素雾化吸入治疗婴儿气管插管导致的喉头水肿疗效显著。
OBJECTIVE: To observe the curative effect of laryngeal edema caused by intubation with 3% hypertonic saline combined with epinephrine nebulization in the treatment of infantile tracheal intubation. Methods: From January 2010 to May 2013, 60 infants with symptoms of laryngeal edema after extubation of mechanical ventilation in our hospital were selected. Randomly divided into control group and treatment group of 30 cases. Treatment group with epinephrine dissolved in 3% hypertonic saline inhalation therapy, the control group with dexamethasone dissolved in 0.9% saline inhalation therapy. The duration of laryngeal edema, respiratory rate and heart rate in two groups were compared. Results: The duration of laryngeal edema was 20.10 ± 7.14 hours in the treatment group and 27.70 ± 4.89 hours in the control group, the difference was statistically significant (P <0.05). Respiratory rate was 35.86 ± 7.92 times / min in the first hour after nebulization, and 40.40 ± 8.70 times / min in the control group. The respiratory rate of the treatment group was lower than that of the control group (P <0.05) ). The heart rate of the treatment group was 146.93 ± 9.67 times / min and that of the control group was 143.03 ± 11.73 times / min. There was no significant difference between the two groups (P> 0.05). Conclusion: 3% hypertonic saline combined with nebulized epinephrine inhalation has significant therapeutic effect on laryngeal edema caused by intubation in infants.