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目的了解乳腺癌患者术前、术后(半年内)、康复期(1年后)3个阶段的焦虑抑郁情绪变化。方法采用汉密尔顿焦虑量表(HAMA)、汉密尔顿抑郁量表(HAMD-17)对术前、术后及康复期各60例患者和60名正常人对照组进行评定。结果乳腺癌患者精神性焦虑因子分术前与术后、术后与康复期都有显著差异(F=14.03,P<0.01);迟缓(F=10.003,P<0.01)、睡眠障碍因子分(F=10.00,P<0.01)和HAMA总分(F=8.297,P<0.01)术前与术后有显著差异;HAMD-17总分术前与术后、康复期有显著差异(F=8.297,P<0.01);与对照组相比,躯体性焦虑因子分(t=8.688,P<0.01)、精神性焦虑因子分(t=12.33,P<0.01)、HAMA总分(t=12.7,P<0.01)、焦虑/躯体性(t=11.97,P<0.01)、认知障碍(t=3.366,P<0.01)、迟缓(t=9.743,P<0.01)、睡眠障碍(t=3.317,P<0.01)、HAMD-17总分(t=14.66,P<0.01)有明显差异。结论乳腺癌患者手术前后有着明显的焦虑、抑郁情绪,术前表现最高,应对其进行适当的干预。
Objective To investigate the changes of anxiety and depression in three stages of breast cancer patients before surgery, after surgery (within half a year) and after rehabilitation (one year). Methods HAMA and HAMD-17 were used to assess the preoperative, postoperative and convalescent levels of 60 patients and 60 normal controls. Results There was a significant difference in mental anxiety factors between preoperative and postoperative, postoperative and convalescent periods in patients with breast cancer (F = 14.03, P <0.01), delayed (F = 10.003, P <0.01) (F = 10.00, P <0.01) and HAMA score (F = 8.297, P <0.01). There was a significant difference in preoperative and postoperative HAMD-17 total scores (T = 12.33, P <0.01), HAMA score (t = 12.7, P <0.01); Compared with the control group, physical anxiety factor score (T = 3.776, P <0.01), anxiety / soma (t = 11.97, P <0.01) P <0.01). The total score of HAMD-17 (t = 14.66, P <0.01) was significantly different. Conclusion The patients with breast cancer have obvious anxiety and depression before and after operation, and have the highest preoperative performance, so they should be properly intervened.