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目的观察血必净注射液对大面积烧伤患者脏器功能损害的保护作用。方法将67例大面积烧伤患者随机分为对照组(34例)和观察组(33例)。两组均给予西医常规治疗,观察组在西医常规治疗的基础上加用血必净注射液静脉滴注,疗程7天。观察两组患者治疗前后肝肾功能、凝血功能,C-反应蛋白含量等变化。结果治疗后观察组肝肾功能、凝血功能明显改善(P<0.05),C-反应蛋白含量降低(P<0.05);观察组肝功能、凝血功能、C-反应蛋白的改善优于对照组(P<0.05)。结论血必净注射液可通过改善凝血功能、降低炎性介质的释放来保护大面积烧伤患者重要脏器的功能。
Objective To observe the protective effect of Xuebijing Injection on organ dysfunction in patients with extensive burn. Methods Sixty-seven patients with extensive burn were randomly divided into control group (34 cases) and observation group (33 cases). Both groups were given routine treatment of Western medicine, the observation group on the basis of conventional Western medicine plus Xuebijing injection intravenous infusion, the course of treatment for 7 days. The changes of liver and kidney function, coagulation function, C-reactive protein content before and after treatment in both groups were observed. Results After treatment, the hepatic and renal function and coagulation function in the observation group were significantly improved (P <0.05), and the content of C-reactive protein was decreased (P <0.05). The liver function, coagulation function and C-reactive protein in the observation group were better than those in the control group P <0.05). Conclusion Xuebijing Injection can protect the function of vital organs in patients with extensive burn by improving the coagulation function and reducing the release of inflammatory mediators.