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目的:分析上呼吸道感染患儿临床抗菌药物使用的合理性,为儿科患者抗菌药物的合理使用提供参考。方法:抽取2015年3月—2016年3月期间1 200例上呼吸道感染患儿为研究对象,对其病例资料进行回顾性调查,分析患儿白细胞计数、抗菌药物的使用情况、用药的合理性以及临床疗效。结果:1 200例上呼吸道感染儿科患者中抗菌药物使用率为67.17%;经口服用药比例为37.97%和注射用药比例为62.03%;不包括氨基糖苷类和氟喹诺酮类抗菌药物;药物利用度指数(DUI)均<1;当患者白细胞计数较低时的抗菌药物使用率较低,白细胞计数超过15×109/L时抗菌药物的使用率明显上升,使用抗菌药物治疗的患儿康复率和有效率显著高于未使用抗菌药物(P<0.05)。结论:合理使用抗菌药物能够有效加快患儿的康复,提高了有效率,确保了患儿的用药安全。
Objective: To analyze the rationality of clinical antibacterials in children with upper respiratory tract infection, and to provide reference for rational use of antibacterials in pediatric patients. Methods: A total of 1,200 children with upper respiratory tract infection during March 2015 to March 2016 were selected as the study subjects. The data of their cases were retrospectively analyzed to analyze the children’s white blood cell count, the use of antimicrobial drugs and the rationality of medication And clinical efficacy. Results: The use rate of antimicrobial agents in 67 pediatric patients with upper respiratory tract infection was 67.17%, 37.97% by oral administration and 62.03% by injection, excluding aminoglycosides and fluoroquinolones. The drug utilization index (DUI) were all less than 1; when the patient’s white blood cell count was low, the usage rate of antimicrobial drugs was low; when the white blood cell count exceeded 15 × 109 / L, the usage rate of antimicrobial drugs increased obviously; The efficiency was significantly higher than that without antibiotics (P <0.05). Conclusion: The rational use of antimicrobial agents can effectively speed up the recovery of children, improve the efficiency and ensure the safety of children’s medication.