We develop an experimental tool to investigate the order parameter of superconductors by combining pointcontact spectroscopy measurement with high-pressure technique.It is demonstrated for the first time that planar point-contact spectroscopy measurement on noncentrosymmetric superconducting PbTaSe2 single crystals is systematically subjected to hydrostatic pressures up to 12.1 kbar.Under such a high pressure,the normal-state contact resistance is sensitive to the applied pressure,reflecting the underlying variation of contact transparency upon pressures.In a superconducting state,the pressure dependence of the energy gap △0 and the critical temperature Tc for gap opening/closing are extracted based on a generalized Blond-Tinkham-Klapwijk model.The gap ratio 2△0/kBTc indicates a crossover from weak coupling to strong coupling in electron pairing strength upon pressure for PbTaSe2.Our experimental results show the accessibility and validity of high-pressure point-contact spectroscopy,offering rich information about high-pressure superconductivity.