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本实验研究不同ｐＨ值及不同量的盐酸（ＨＣｌ）气管内注入致家兔急性肺损伤模型，Ａ、Ｂ、Ｃ３组（ｎ均为８）家兔麻醉后气管内分别注入ｐＨ＝１．５，２．５ｍｌ／ｋｇ；ｐＨ＝１，２．５ｍｌ／ｋｇ；ｐＨ＝１，２ｍｌ／ｋｇ体重的ＨＣｌ，吸纯氧定压机械通气，气道压维持２．０ｋＰａ，当ＰａＯ２持续低于１３．３ｋＰａ时认为模型形成。结果Ｂ组平均动脉压变化率最大［Ａ组（１１．３３±１２．１０）％，Ｂ组（４１．４４±２４．２５）％，Ｃ组（１３．２５±１２．０１）％，Ｐ＜０．０５］，模型形成时间Ａ组最长（Ａ组３０２．５±６０、１ｍｉｎ，Ｂ组１０．０±５．０ｍｉｎ，Ｃ组３５．６±１１．０ｍｉｎ，Ｐ＜０，０１），模型形成后２ｈ内死亡率Ｂ组最高（Ａ组０／８，Ｂ组６／８，Ｃ组１／８，Ｐ＜０．０５），模型形成后血气值Ｂ组不如Ａ、Ｃ组稳定（Ｐ＜０．０５），肺动态顺应性Ｂ组最低［Ｐ＜０．０１，Ａ组５．７５±０．１７ｍｌ／（ｋＰａ·ｋｇ），Ｂ组３．６８±０．３７ｍｌ／（ｋＰａ·ｋｇ），Ｃ组４．４３±０．５０ｍｌ／（ｋＰａ·ｋｇ）］。通过３组结果可得出以下结论：气管内注入ｐＨ＝１，２ｍｌ／ｋｇ体重ＨＣｌ致急性肺损伤模型，模型形成时间短，死亡率低，模型?
The experimental study of different pH values and different concentrations of hydrochloric acid (HCl) intratracheal injection of acute lung injury in rabbits model, A, B, C3 group (n are 8) after intratracheal intratracheal injection of pH = 1.5 , 2.5ml / kg; pH = 1,2.5ml / kg; pH = 1,2ml / kg body weight of HCl, suction pure oxygen constant pressure mechanical ventilation, airway pressure maintained 2.0kPa, 3.kPa considered the formation of the model. Results The change rate of mean arterial pressure was the highest in group B (11.33 ± 12.10% in group A, 41.44 ± 24.25% in group B and 13.25 ± 12.01% in group C, P <0.05]. The time of model formation was the longest in group A (302.5 ± 60,1min in group A, 10.0 ± 5.0min in group B and 35.6 ± 11.0min in group C, P <0,01) , The mortality was highest in group B within 2 hours after model formation (group A, group A, group B, group B, group B, group C, group C, group A and group C) (P <0.05). The dynamic compliance of lung in group B was the lowest (P <0.01, 5.75 ± 0.17ml / (kPa · kg) in group A and 3.68 ± 0.37ml / (kPa · Kg), C group 4.43 ± 0.50ml / (kPa · kg)]. The following three conclusions can be drawn: Intratracheal injection of pH = 1,2 ml / kg body weight of HCl induced acute lung injury model, the formation of a short time, low mortality, the model?