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很多学者对幼儿铅中毒、缺铁和铅毒性之间的关系进行了研究。Six和Goyer报导:在缺铁情况下,大鼠饮用含200 ppm铅的饮水为期十周,可能因铅的吸收和运转的增加,致使大鼠肝、肾和骨骼中铅滞留增加。Conrad和Barton指出:当大鼠摄铁量增加时,~(203)Pb的吸收量减少。作者先前报导了饲料中含过量的铁和抗坏血酸对大鼠镉中毒的防治效果及预防大鼠急性铅中毒的效果。本实验又就铁和抗坏血酸是否具有防治大鼠亚急性铅中毒的效果问题进行了研究。雄性大鼠随机分为四组,每组9或10只。第一组鼠饲以基础饲料,第二组鼠饲以含铅饲料(基础饲料中加500 ppm的铅),第四组鼠饲
Many scholars have studied the relationship between childhood lead poisoning, iron deficiency and lead toxicity. Six and Goyer reported that drinking 10 ppm of lead in drinking water for 10 weeks in the absence of iron may lead to increased lead retention in rat liver, kidney and bone due to increased lead uptake and turnover. Conrad and Barton pointed out that when the amount of iron in rats increased, the absorption of ~ (203) Pb decreased. The authors previously reported the effect of diet containing excess iron and ascorbic acid on the prevention and treatment of cadmium poisoning in rats and the prevention of acute lead poisoning in rats. In this study, the effect of iron and ascorbic acid on the prevention and treatment of subacute lead poisoning in rats was also studied. Male rats were randomly divided into four groups, each group of 9 or 10. The first group was fed the basal diet, the second group was fed the lead diet (500 ppm lead in the basal diet), the fourth group was fed