作者认为一个有效药物往往是偶然发现的。但如能指出抗血吸虫作用可能的靶点或许是有帮助的。作者分8个部分叙述。1. 葡萄糖/糖原的代谢:虫依赖于葡萄糖的大量分解代谢,葡萄糖通过 Embden-Myerhof 途径被利用,乳酸为其主要副产物。这途径的1:3二磷酸甘油酸转变成3-磷酸甘油,及磷酸烯醇丙酮酸到丙酮酸的两步而产生 ATP。 The authors believe that an effective drug is often discovered by chance. However, it may be helpful to point out the possible targets of anti-schistosome action. The author is divided into 8 parts. 1. Glucose / Glycogen Metabolism: Bugs rely on massive catabolism of glucose, which is utilized by the Embden-Myerhof pathway, a major byproduct of lactate. This pathway converts 1: 3 diphosphoglycerate to 3-phosphoglycerol, and two steps of phosphoenolpyruvate to pyruvate produce ATP.