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目的:通过药物利用评价(drug utilization evaluation,DUE)方法,评价比阿培南临床使用的合理性与规范性,为促进临床合理用药提供参考。方法:依据“比阿培南DUE标准”对某医院2014年住院患者使用比阿培南332例病历进行回顾性分析。结果:(1)抗菌药物管理:微生物送检率82.2%(80%),会诊流程符合率51.3%(100%),病程记录符合率83.4%(100%),处方权限符合率97.3%(100%);(2)用药指征:适应症98.2%(90%);(3)用药过程:给药途径、溶媒选择、配伍禁忌正确率100%(100%);疗效监测项符合率80.4%(85%);(4)用药结果有效率78.6%(80%)。结论:医院比阿培南临床使用整体情况较好,但仍存在一些不足,医院应针对存在问题进行干预和整改,确保抗菌药物的规范合理使用。“比阿培南DUE标准”对促进临床规范、合理使用比阿培南有一定作用。
OBJECTIVE: To evaluate the rationality and standardization of biapenem in clinical application through the method of drug utilization evaluation (DUE), and to provide a reference for the promotion of clinical rational drug use. Methods: A retrospective analysis of 332 cases of biapenem using inpatients in a hospital based on the Bienamide DUE Criteria was conducted. Results: (1) Antimicrobials management: The rate of biopsy was 82.2% (80%), the coincidence rate of consultation was 51.3% (100%), the coincidence rate of course record was 83.4% (100% %); (2) indications for medication: indications 98.2% (90%); (3) medication process: the route of administration, solvent selection, incompatibility compatibility 100% (100% (85%); (4) medication results effective rate of 78.6% (80%). Conclusion: The overall clinical use of biapenem in the hospital is better overall, but there are still some shortcomings. The hospital should intervene and rectify the existing problems so as to ensure the rational use of antibacterials. “Biapenem DUE standard ” to promote clinical norms, the rational use of biapenem has a certain effect.