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目的探讨有关抗感染药物不宜混合静滴的溶媒配伍。方法查询《306种注射剂临床配伍应用检索手册》中有关抗感染药物配伍的项目及检索《中国药学文摘》中有关抗感染药物配伍试验的报道。结果有70抗感染药物不宜与部分溶媒直接混合静滴。结论有些抗感染药物与溶媒混合可能导致降效变色沉淀等而影响疗效,临床使用时应合理选择。
Objective To explore the compatibility of anti-infective drugs should not be mixed intravenous solvent compatibility. Methods To search for the articles about the compatibility of anti-infectives in the Handbook of Clinical Compatibility and Application of 306 Injections and to search the Chinese Pharmaceutical Abstracts for the compatibility testing of anti-infectives. The results of 70 anti-infective drugs should not be mixed directly with some intravenous infusion. Conclusion Some anti-infective drugs mixed with vehicle may lead to the effect of discoloration, such as discoloration, which should be considered in clinical practice.