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我们对15例多发性骨髓瘤患者进行尿沉渣中骨髓瘤细胞及NAG(N-乙酰-β-氨基葡萄糖苷酶)的检测,发现7例初诊患者尿中出现骨髓瘤细胞并伴有NAG的升高,其中有4例患者尿中骨髓瘤细胞成团存在,尿中未检出骨髓瘤细胞的8例患者中也有4例尿NAG升高。本研究标本用量少,方法简便易行,便于临床应用。对一些诊断未明的肾病或肾移植前以及疑诊为多发性骨髓瘤患者可作为常规检测手段,而且比尿本-周蛋白更具有诊断价值。
In 15 cases of multiple myeloma patients with urinary sediment cells and NAG (N-acetyl-β-glucosaminidase) test found that 7 cases of newly diagnosed patients with myeloma cells in the urine and accompanied by the rise of NAG In 4 of 8 patients with urinary myeloma cells in the urine, 4 of 8 patients with no detectable myeloma cells also had elevated urinary NAG. This study specimens with less dosage, the method is simple and easy to facilitate clinical application. For some unknown nephropathy or renal transplant and suspected patients with multiple myeloma can be used as a routine test, but also more than the urine of the week of the protein is more diagnostic value.