Differential effects of controlled hypotension on gastric intramucosal pH and post-operational gastr

来源 :Journal of Nanjing Medical University | 被引量 : 0次 | 上传用户:nwwwdff
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Objective:To observe the effects of controlled hypotension on gastric intramucosal pH and post-operational gastrointestinal functions using two specific anesthesia methods.Methods:Thirty patients(ASAⅡ)scheduled for ectomy of hepatocarcinoma,were randomly assigned to two groups:epidural block combined with intravenous anesthesia group(E group)and inhalation anesthesia group(G group).Gastric PgCO2 and pHi were monitored at different time points,before theintravenous induction of controlled hypotension,after 1 h and2 h,and 1 h after the termination of controlled hypotension.In the meanwhile,the artery blood gas was analyzed.Results:There was no significant difference in blood gas indexes between E group and G group.However,pHi decreased significantly after 1 h and 2 h of controlled hypotension(P <0.05),and during the same periods PgCO2 increased significantly(P <0.05 or P <0.01),the time of bowelm ovement and defecating deferred significantly shorter in G group patients,when compared with E group patients.Conclusion:Epidural block in combination with general anesthesia can improve gastrointestinal blood flow during controlled hypotension and facilitates post-operational recovery of gastrointestinal functions. Objective: To observe the effects of controlled hypotension on gastric intramucosal pH and post-operational gastrointestinal functions using two specific anesthesia methods. Methods: Thirty patients (ASA II) scheduled for ectomy of hepatocarcinoma, were randomly assigned to two groups: epidural block combined with intravenous anesthesia group (E group) and inhalation anesthesia group (G group). Gastric PgCO2 and pHi were monitored at different time points, before the indravenous induction of controlled hypotension, after 1 h and 2 h, and 1 h after the termination of controlled hypotension. The meanwhile, the artery blood gas was analyzed. Results: There was no significant difference in blood gas indexes between E group and G group. Less, pHi marked significantly after 1 h and 2 h of controlled hypotension (P <0.05), and during the same period PgCO2 increased significantly (P <0.05 or P <0.01), the time of bowel movement and defecating deferred significantly shorter in G group patients, when compared wi th E group patients. Conclusion: Epidural block in combination with general anesthesia can improve gastrointestinal blood flow during controlled hypotension and facilitates post-operational recovery of gastrointestinal functions.
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