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目的观察黄芪四君子汤联合干扰素-a治疗慢性乙型肝炎的临床疗效。方法根据病毒性肝炎诊断标准选择初诊慢性乙型肝炎患者,血清学检查符合干扰素-a用药指征,治疗组给予黄芪四君子汤联合干扰素-a,对照组单用干扰素-a,疗程均为48 W。结果治疗组可以较快改善症状、体征、肝脏炎症(P<0.05)、降低病毒载量(P<0.05),以及升高白细胞。结论黄芪四君子汤联合干扰素-a治疗慢性乙型肝炎患者具有较好的临床疗效,优于单用干扰素-a,可改善临床症状、提高临床疗效、并可减轻干扰素-a的副作用。
Objective To observe the clinical efficacy of Astragalus Sijunzi Decoction combined with interferon-a in the treatment of chronic hepatitis B. Methods According to the diagnostic criteria of viral hepatitis in patients with newly diagnosed chronic hepatitis B, serological examination in line with interferon-a medication indications, the treatment group given Astragalus Sijunzi Decoction combined with interferon-a, the control group with interferon-a, treatment were 48 W Results The treatment group could quickly improve symptoms, signs, liver inflammation (P <0.05), reduce the viral load (P <0.05), and increase leukocytes. Conclusion Astragalus Sijunzi Decoction combined with interferon-a treatment of patients with chronic hepatitis B has better clinical efficacy, better than interferon-α alone can improve clinical symptoms, improve clinical efficacy, and reduce the side effects of interferon-a.