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随着围产医学的发展,危重新生儿尤其是早产儿及极低出生体重儿的存活率明显上升。由于新生儿免疫功能尚未发育成熟等原因,感染仍然是目前面临的重要问题,并对新生儿预后造成严重危害。由于新生儿的高感染易感性以及新生儿感染时临床症状的不典型性和多样性,使得早期诊治成为改善患儿预后的关键。脐血及羊水检测具有早期、无创伤、安全、方便的优点。该文主要探讨脐血及羊水炎性标志物联合检测在新生儿早发型败血症中的临床应用。
With the development of perinatal medicine, the survival rate of critically ill newborns, especially premature infants and those with very low birth weight has remarkably increased. As the newborn immune function has not yet matured and other reasons, infection is still an important issue now facing, and the prognosis of newborns caused serious harm. Due to the high neonatal infection susceptibility and atypical clinical symptoms of neonatal infection and diversity, making early diagnosis and treatment as the key to improving the prognosis of children. Umbilical cord blood and amniotic fluid testing with early, non-invasive, safe and convenient advantages. This article mainly discusses the clinical application of cord blood and amniotic fluid markers combined detection in early neonatal sepsis.