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前列腺素E_2(PGE_2)是巨噬细胞、淋巴细胞和某些肿瘤细胞的产物,可提高或抑制细胞介导的免疫反应,如淋巴细胞的增殖、细胞毒性和细胞活性产物.肺是PGE_2产生的主要场所之一。作者测定了肺癌患者支气管肺泡灌洗液(BALF)中PGE_2水平,以揭示PGE_2抑制肺组织局部免疫反应在肺癌发生发展中的作用。研究对象为男34例:18例为原发性肺癌患者,其中鳞癌9例,腺癌4例,小细胞癌5例,年龄43～78
Prostaglandin E 2 (PGE 2 ) is a product of macrophages, lymphocytes, and certain tumor cells that can increase or inhibit cell-mediated immune responses, such as lymphocyte proliferation, cytotoxicity, and cellular activity products. The lung is produced by PGE 2 One of the main places. The authors measured PGE 2 levels in bronchoalveolar lavage fluid (BALF) from patients with lung cancer to reveal the role of PGE 2 in inhibiting local lung immune response in the development of lung cancer. The subjects were male 34 patients: 18 patients with primary lung cancer, including 9 cases of squamous cell carcinoma, 4 cases of adenocarcinoma, 5 cases of small cell carcinoma, age 43 to 78