1　过敏反应患者 ,女 ,38岁 ,因小腿急性疏松结缔组织炎给予克林霉素磷酸酯 1 .2ｇ·ｄ 1 ,静脉滴注 ,用药 3ｄ患者全身出现皮疹 ,瘙痒明显 ,并伴有胸闷、气促、腹部隐痛等症状。即停药给予抗过敏治疗 ,2ｄ后皮疹逐渐消退[1 ] 。患者 ,男 ,35岁 ,因上呼吸道感染给予克林霉素磷 1 allergic patients, female, 38 years old, due to acute loose connective tissue inflammation given clindamycin phosphate 1. 2g · d 1, intravenous drip, medication 3d patients with systemic rash, itching obvious, accompanied by chest tightness, Shortness of breath, abdominal pain and other symptoms. That withdrawal to give anti-allergy treatment, 2d after the rash subsided [1]. The patient, male, 35 years old, received clindamycin phosphate for upper respiratory tract infection