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目的探讨过敏性紫癜患儿血小板平均体积大小与出现消化道症状的关系。方法对2009年～2010年6月在本院住院的50例过敏性紫癜患儿的血小板平均体积及临床上有无消化道症状进行回顾性分析,选取50例健康患儿作为正常对照。结果①50例过敏性紫癜患儿中出现消化道症状的有27例,占54%;②过敏性紫癜患儿的血小板平均体积为(7.7±0.6),正常对照组为(8.0±0.5),过敏性紫癜患儿的血小板平均体积比正常对照组小;③27例出现消化道症状的过敏性紫癜患儿血小板平均体积为(6.9±0.9),23例无消化道症状患儿的血小板平均体积为(7.8±0.5),有消化道症状的过敏性紫癜患儿的血小板平均体积比无消化道症状患儿的小。提示过敏性患儿血小板平均体积越小越容易出现消化道症状(P<0.01)。结论过敏性紫癜患儿血小板平均体积越小越容易出现消化道症状,血小板平均体积可作为过敏性紫癜患儿临床治疗监测指标之一。
Objective To investigate the relationship between the average platelet volume and gastrointestinal symptoms in children with Henoch-Schonlein purpura. Methods A retrospective analysis was performed on the average platelet volume and the presence or absence of gastrointestinal symptoms in 50 children with Henoch-Schonlein purpura hospitalized in our hospital from 2009 to June 2010, and 50 healthy children were selected as normal controls. Results ① There were 27 cases (54%) of gastrointestinal symptoms in 50 cases of Henoch-Schonlein purpura; ② The average platelet volume of children with Henoch-Schonlein purpura was (7.7 ± 0.6) and (8.0 ± 0.5) The average volume of platelets in children with purpura was smaller than that in the normal control group. The average volume of platelets in children with Henoch-Schonlein purpura was (6.9 ± 0.9) in 27 cases, and the mean platelet volume in 23 children without digestive symptoms was ( 7.8 ± 0.5), children with gastrointestinal symptoms of Henoch-Schonlein purpura, the average volume of platelets than children without gastrointestinal symptoms of small. Prompt allergic children with smaller average volume of platelets more prone to gastrointestinal symptoms (P <0.01). Conclusions Children with Henoch-Schonlein purpura are more likely to have gastrointestinal symptoms when the average platelet volume is smaller. The mean platelet volume can be used as one of the clinical indicators for the treatment of Henoch-Schonlein purpura in children.