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印度安德拉邦北部和东北部的山林部族地带属疟疾高发区。1980年,安德拉邦卫生当局制定了一个应急规划,让分属5个不同地区的8个基层卫生中心所辖的51 325人全民服药,以期大幅度降低人群患病率。本文总结了这次实验的结果。在间日疟流行区及恶性疟流行区,分别给予成人氯喹单剂量600mg(基质)或氯喹600mg(基质)加伯喹45mg(基质),按以下方法进行: 1.在81年发病最低时服第一轮药(多在2月份,最晚4月份),随后开始雨季前的喷洒灭蚊。2.根据传播潜势在2或3个月后再服
The forested tribal belt in northern and northeastern Andhra Pradesh, India, is a high incidence of malaria. In 1980, the Andhra Pradesh health authorities developed a contingency plan to allow 51,325 people under the jurisdiction of eight primary health centers in five different regions to take their medicine in full, with a view to drastically reducing the prevalence among the population. This article summarizes the results of this experiment. In the Vivax and Plasmodium falciparum areas, single doses of adult chloroquine 600 mg (matrix) or chloroquine 600 mg (matrix) plus carbenoxol 45 mg (matrix) were given as follows: 1. At the lowest incidence in 81 years The first round of drug (mostly in February, latest April), followed by the rainy season before spraying mosquito control. 2. After 2 or 3 months depending on the spreading potential