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目的探讨支气管镜氩等离子体凝固(argon plasma coagulation,APC)对管腔内肺癌患者呼吸功能的影响和治疗安全性。方法对35例经支气管镜检查病理确诊的管腔内肺癌患者行APC治疗,对治疗前后呼吸功能(肺功能、动脉血氧分压)、体力状况评分、气道阻塞再通进行分析。结果经支气管镜APC治疗后,呼吸功能和体力状况评分有显著改善,气道再通有效率高(总有效率94.29%),治疗过程中没有发生严重并发症。结论支气管镜APC治疗能改善管腔内肺癌患者呼吸功能和生活质量,是治疗管腔内肺癌安全有效的方法。
Objective To investigate the effect of argon plasma coagulation (APC) on the respiratory function of lung cancer patients and the safety of the treatment. Methods APC was performed in 35 patients with luminal lung cancer diagnosed by bronchoscopy. Respiratory function (pulmonary function, arterial oxygen tension), physical status scores and recanalization of airway before and after treatment were analyzed. Results After bronchoscopic APC treatment, respiratory function and physical status score improved significantly, airway recanalization efficiency (total effective rate 94.29%), no serious complications occurred during the treatment. Conclusion Bronchoscopy APC can improve the respiratory function and quality of life in patients with intraluminal lung cancer. It is a safe and effective method for the treatment of intraluminal lung cancer.