论文部分内容阅读
目的分析唐山市丰润区2015年疫苗不良反应的发生特性及影响因素。方法通过全国疑似预防接种异常反应信息管理系统,收集唐山市丰润区疫苗不良反应的个案数据。采用描述性流行病学方法进行分析并判断发生原因。结果唐山市丰润区2015年共报告不良反应个案38例,其中一般反应34例(占89.47%),异常反应4例(占10.53%)。男女比例为1.53∶1。临床诊断为发热17例(占44.73%),红肿12例(占31.58%),硬结5例(占13.16%),过敏性皮疹4例(占10.53%)。报告及时率和调查及时率均为100.00%。接种疫苗分布中,吸附无细胞百白破联合疫苗25例(占65.79%),冻干甲型肝炎减毒活疫苗4例(占10.53%),A群脑膜炎球菌多糖疫苗3例(占7.89%),其他疫苗6例(15.78%)。接种后0~1 d报告6例(占15.78%),接种后1~d报告27例(占71.05%),接种后2~d报告5例(占13.16%)。结论疫苗种类、疫苗注射剂量、疫苗注射途径、时间间隔对唐山市丰润区不良反应的发生有关。
Objective To analyze the incidence and influencing factors of 2015 vaccine adverse reaction in Fengrun District of Tangshan City. Methods Through the national information system of suspected anaphylaxis vaccination, the case data of vaccine adverse reactions in Fengrun District of Tangshan City were collected. Descriptive epidemiological methods were used to analyze and determine the cause. Results A total of 38 cases of adverse reactions were reported in Fengrun District of Tangshan City in 2015, of which 34 were general reactions (89.47%) and 4 were abnormal reactions (10.53%). The male-female ratio is 1.53: 1. Clinical diagnosis of fever in 17 cases (44.73%), 12 cases of inflamed (31.58%), induration in 5 cases (13.16%), allergic rash in 4 cases (10.53%). The report promptly rate and timely investigation rate are 100.00%. In the distribution of vaccination, there were 25 cases (65.79%) with cell-free baPb vaccine, 4 cases with live-attenuated hepatitis A attenuated vaccine (10.53%), 3 cases with group A meningococcal polysaccharide vaccine (accounting for 7.89 %), Other vaccines in 6 cases (15.78%). 6 cases (15.78%) were reported 0 ~ 1 d after inoculation, 27 cases (71.05%) were reported 1 ~ d after inoculation and 5 cases (13.16%) were reported 2 ~ d after inoculation. Conclusion The types of vaccine, the dose of vaccine, the route of vaccine injection and the time interval are related to the occurrence of adverse reactions in Fengrun District of Tangshan City.