论文部分内容阅读
目的:观察单纯切除、新鲜羊膜移植与自体角膜缘上皮联合球结膜移植治疗翼状胬肉的临床疗效。方法:随机选择翼状胬肉患者共48例（48只眼）,随机分为一组（胬肉单纯切除）,二组（胬肉切除联合新鲜羊膜移植）三组（自体角膜缘上皮联合球结膜移植）,观察术后角膜愈合、角膜缘新生血管及球结膜是否有结膜翼状胬肉样组织增生。结果:随访 3月-25月,一组16例5例复发（31％）;二组1例复发（6.2％）;三组无1例复发。结论:单纯的手术切除不能从根本上阻止翼状胬肉的复发。羊膜移植目的在于恢复角膜缘基质微环境,而角膜缘干细胞移植在于恢复角膜缘干细胞的数量,因而,两种手术方法均可行。但角膜缘上皮联合结膜移植手术方式系自体眼表组织移植,手术简便安全,成功率高,是处理翼状胬肉复发的最佳手术方式。
Objective: To observe the clinical effect of simple excision, fresh amniotic membrane transplantation and limbal epithelial conjunctival transplantation for the treatment of pterygium. Methods: A total of 48 patients (48 eyes) with pterygium were randomly divided into three groups (pterygium resection alone), two groups (pterygium excision combined with fresh amniotic membrane transplantation), three groups (autologous limbal epithelial conjunctiva Transplantation), observe the corneal healing, corneal limbal neovascularization and conjunctival conjunctival pterygium whether or not tissue hyperplasia. Results: Followed up from March to 25 months, a group of 16 cases of 5 cases of recurrence (31%); two cases of one case of recurrence (6.2%); three cases without recurrence. Conclusion: Surgical resection alone can not fundamentally prevent the recurrence of pterygium. Amniotic membrane transplantation aims to restore limbal stroma microenvironment, and limbal stem cell transplantation is to restore the number of limbal stem cells, therefore, both surgical methods are feasible. However, corneal limbal epithelial conjunctiva transplantation surgery is autologous ocular surface tissue transplantation, operation simple and safe, high success rate, is the best surgical treatment of recurrence of pterygium.