目的:研究和比较衍生自大肠杆菌外膜蛋白A(outer membrane protein A,OmpA)信号肽的多肽P-KKK在体外对标准细菌株及临床分离耐药菌株的杀菌活性,为研发新型抗菌药物提供重要信息。方法:(1)衍生肽的设计:依据大肠杆菌OmpA信号肽(P-AQA)的一级结构MKKTAIAIAVALAGFATVAQA(蛋氨酸-赖氨酸-赖氨酸-苏氨酸-丙氨酸-异亮氨酸-丙氨酸-异亮氨酸-结氨酸-
Unexplained Iron Deficiency Anemia (IDA) is known to be attributed to abnormal blood loss from lesions in the parts of gastrointestinal tract that are difficult