目的：探讨淡色库蚊３个抗性品系对５种化学杀虫剂的交互抗性，为合理使用杀虫剂提供依据。方法：采用ＷＨＯ标准生物测定法。结果：抗ＤＤＶＰ品系达１４４７倍的抗性，而对氯氰菊酯、残杀威的交互抗性分别为２０７２７倍和８９６倍，对溴氰菊酯基本没有交互抗性，对ＤＤＴ为０１７倍，呈负交互抗性。抗残杀威品系达６９３倍抗性，对氯氰菊酯、ＤＤＶＰ的交互抗性为８５６倍、３２７倍，对ＤＤＴ基本无交互抗性，对溴氰菊酯呈负交互抗性。抗氯氰菊酯品系达５０１１１倍的抗性，对溴氰菊酯、ＤＤＴ的交互抗性为６１０倍及８５５倍，而对ＤＤＶＰ、残杀威基本无明显交互抗性。结论：长期使用一种杀虫剂易产生抗性，亦可能对其他杀虫剂产生交互抗性，用药时应注意种类的选择 Objective: To investigate the cross resistance of three resistant strains of Culex pipiens pallens to five kinds of chemical insecticides to provide the basis for the rational use of insecticides. Methods: The WHO standard bioassay. RESULTS: The anti-DDVP strain was 1447-fold resistant, while the resistance to cypermethrin and propoxur was 20727 and 896 times, respectively. There was no cross-resistance to deltamethrin. DDT was 0  17 times, was negative interactive resistance. Resistant malachite strain reached 6  93 times resistance, resistance to cypermethrin, DDVP was 856 times, 327 times, almost no cross-resistance to DDT, deltamethrin negative interaction. Resistance to cypermethrin was 50111-fold, with 610-fold and 855-fold resistance to deltamethrin and DDT, respectively. However, there was no obvious cross-resistance to DDVP and propoxur. Conclusion: Long-term use of an insecticide is resistant to development and may also cause resistance to other insecticides. Care should be taken when selecting drugs