斑马鱼具有繁殖能力强、体外受精发育、胚胎透明、性成熟周期较短、个体小、遗传基因与人类相似等诸多特点,作为一种模式生物正逐渐拓展到生命体的各个系统。目前已经广泛用于人类疾病模型的建立、新药研发和药物的筛选等方面。此外,斑马鱼还被应用于毒理学、发育生物学和遗传学等的研究。斑马鱼在科学研究的多方面均展现了广阔前景,该文主要从斑马鱼模式的研究现状及其应用情况进行综合阐述。 Zebrafish reproductive ability, in vitro fertilization, embryo transparency, sexual maturity cycle is short, small, genetic and human similarities and many other features, as a model organism is gradually extended to the life of the various systems. Has been widely used in the establishment of human disease models, drug development and drug screening and so on. In addition, zebrafish are also used in toxicology, developmental biology and genetics research. The zebrafish has broad prospects in many aspects of scientific research. This article mainly elaborates the current research situation and its application of zebrafish patterns.