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正常人体每天骨髓能产生上百亿个新的血细胞,大多数为红细胞。而患有白血病的人产生的白细胞比实际需要的多,且多数的白细胞是不正常,其存活期比正常细胞长。尽管这种白细胞数量很大,然而却不能像正常白细胞那样抗感染。体内这种白细胞的增多,会直接影响一些重要器官的功能,同时影响正常健康血细胞的产量。根据白血病的自然病程及骨髓中原始细胞的分化程度,又可分为急性和慢性白血病。急性白血病起病急,病程短,未经治疗大约在6个月内死亡,骨髓和周围血中以异常的原始及早期幼稚细胞(白血病细胞)为主,原始细胞常超过20%。而慢性白血病起病缓慢,自然病程一般在一年以上,骨髓及周围血中以异常但接近成熟的白细胞增多为主。我国急性和慢性白血病的发病率之比为4:1,和亚洲各国
Normal human bone marrow can produce tens of billions of new blood cells, most of them red blood cells. Leukemias, on the other hand, produce more white blood cells than is actually needed, and most white blood cells are abnormal and survive longer than normal cells. Although the number of white blood cells is large, they are not as resistant as normal white blood cells. This increase in white blood cells in vivo, will directly affect the function of some important organs, while affecting the production of normal healthy blood cells. According to the natural course of leukemia and bone marrow in the differentiation of primitive cells, can be divided into acute and chronic leukemia. The acute onset of acute leukemia, short course, died within about 6 months without treatment, bone marrow and peripheral blood abnormal primary and early naive cells (leukemic cells), the original cells often more than 20%. The slow onset of chronic leukemia, the natural course of the disease is generally more than one year, bone marrow and peripheral blood in the abnormal but near-mature white blood cells based. The incidence of acute and chronic leukemia in our country is 4: 1, and in all Asian countries