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百草枯是一种广谱除草剂,毒力强,毒性长,经消化道、呼吸道和皮肤吸收后,迅速分布于全身,对心、肝、肾、肺等多器官有较强的损害,尤以肺脏受损最为严重,通常肺纤维化发生在中毒后5~9天,2~3周达到高峰,最终可因弥漫性肺纤维化导致呼吸衰竭死亡[1]。目前缺乏特效解毒剂,急性百草枯中毒死亡率可高达60%~80%[2]。2014年1月我科收治1例急性重度口服百草枯中毒的患者,病情危重,出现并发症多,经积极救治和精心护理,为后续
Paraquat is a broad-spectrum herbicide with strong toxicity and long toxicity. It is absorbed rapidly through the digestive tract, respiratory tract and skin. It is rapidly distributed throughout the body and causes great damage to many organs such as heart, liver, kidney and lung. The most severe lung damage, pulmonary fibrosis usually occurs 5 to 9 days after poisoning, 2 to 3 weeks to reach the peak, eventually leading to respiratory failure due to diffuse pulmonary fibrosis [1]. The current lack of special antidote, acute paraquat poisoning mortality can be as high as 60% to 80% [2]. In January 2014, our department admitted 1 patient with acute severe oral paraquat poisoning who was in critical condition with many complications. After active treatment and meticulous care,