糖尿病是急性冠脉综合征发生、发展以及预后不良的重要因素。许多生物标记物对合并糖尿病的急性冠脉综合征患者的诊断及预后评价具有独特的意义,现对该类患者的心脏标记物如白介素-6、C反应蛋白、胎盘生长因子、纤维蛋白原、髓过氧化物酶、基质金属蛋白酶、脑钠肽、CD40及配体及E选择素等按照炎症、神经内分泌、血栓形成、内皮功能等类别进行综述。 Diabetes is an important factor for the occurrence and development of acute coronary syndrome and poor prognosis. Many biomarkers have unique meanings in the diagnosis and prognosis of patients with acute coronary syndromes complicated with diabetes. The cardiac markers such as interleukin-6, C-reactive protein, placental growth factor, fibrinogen, Myeloperoxidase, matrix metalloproteinase, brain natriuretic peptide, CD40 and ligand and E-selectin were reviewed according to the categories of inflammation, neuroendocrine, thrombosis and endothelial function.