研究冠心病发病机理和寻找治疗冠心病的药物越来越引起人们重视,自从 Anitschkow等首次通过喂饲胆固醇的方法在家兔诱导形成高脂血症和动脉粥样硬化动物模型以来,许多新的动物模型相继产生,如给家兔和大鼠静脉注射兔血清β-脂蛋白。给大鼠静脉注射蛋黄和丙烯胺或注射表面活性剂 triton 以及给予狗、大鼠α-受体拮抗 More and more attention has been paid to the study of the pathogenesis of coronary heart disease and the search for the treatment of coronary heart disease. Since Anitschkow et al first introduced animal models of hyperlipidemia and atherosclerosis in rabbits by feeding cholesterol, many new Animal models have been generated, such as rabbit and rat intravenous injection of rabbit serum β-lipoprotein. Rats were intravenously injected with egg yolk and acrylamide or with the injection of the surfactant triton and with the dog, rat a-receptor antagonist