【摘 要】
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The design of three novel fatty nitrogen mustard-based anticancer agents with fluorophores incor-porated into the alkene structure(CXL 118,CXL121,and CXL122)is described in this report.The results indicated that these compounds are selectively located in
【机 构】
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Department of Thyroid Surgery,West China Hospital of Sichuan University,Chengdu 610041,China;Departm
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The design of three novel fatty nitrogen mustard-based anticancer agents with fluorophores incor-porated into the alkene structure(CXL 118,CXL121,and CXL122)is described in this report.The results indicated that these compounds are selectively located in lysosomes and exhibit effective antitumour activity.Notably,these compounds can directly serve as both reporting and imaging agents in vitro and in vivo without the need to add other fluorescent tagging agents.
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