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我院1989年以来采用脑立体定向术治疗难治性癫痫11例,其中6例伴有严重精神障碍,初步获得满意结果,现报告如下: 病例选择:各类癫痫明显诊断后,经正规系统的抗痫药物治疗2年以上无效;癫痫发作频繁,每月发作4次以上,病程3年以上者为治疗对象。本组男性9例,女性2例,年龄17～28岁,平均年龄25岁。原因不明性癫痫7例,脑炎后癫痫3例,头外伤后癫痫1例。本组11例中癫痫大发作10例,其中6例伴有精神障碍。精神运动性发作1例。10例不同程度的智力低下。11例患者均作了心理测验:韦氏智力测验,智商0～82分。个性调查:8例显示心理功能部分障碍,有3例检查不合作。脑电图描记:轻度异常6例,中度异常4
11 cases of refractory epilepsy were treated with stereotactic brain surgery since 1989 in our hospital, of which 6 cases were accompanied with severe mental disorders and initially obtained satisfactory results. The report is as follows: Case Selection: After various types of epilepsy are obviously diagnosed, Anti-epileptic drug therapy for more than 2 years invalid; epileptic seizures frequent, more than 4 episodes per month, duration of 3 years or more for the treatment of patients. The group of 9 males and 2 females, aged 17 to 28 years, mean age 25 years. 7 cases of unexplained epilepsy, 3 cases of epilepsy after encephalitis, and 1 case of epilepsy after head trauma. The group of 11 cases of epileptic seizures in 10 cases, of which 6 cases with mental disorders. One episode of psychomotor attack. 10 cases of different levels of mental retardation. All 11 patients underwent psychological tests: Wechsler Intelligence Test, IQ 0-82. Personality survey: 8 cases showed some obstacles to mental function, 3 cases did not check cooperation. Electroencephalography: mild abnormalities in 6 cases, moderate abnormalities 4