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1992年郑州发生了700余例急性砷中毒,对我院收治的108例患者于中毒初期全部描记了ECG并作动态观察。71例(65.7%)出现ST-T改变,主要是T波异常,呈倒置、双峰、平顶和低平及Q-Tc延长,严重者有ST段压低(0.05~0.20mv)其中27例(25%)ECC诊断“心肌受损”。ECG异常改变程度与同期尿砷含量测量结果呈线性相关(r=0.617.P<0.01).T波改变没有区域性特征。ECG诊断低血钾13例。与心肌受损并存者仅4例,与同期血清钾测定结果基本吻合,而与同期尿砷含量测定结果相关性不显著。提示及时全面描记ECC和动态观察能为急性砷中毒的抢救治疗提供重要参考依据。
In 1992, more than 700 cases of acute arsenic poisoning occurred in Zhengzhou, and 108 patients admitted to our hospital were all marked with ECG at the initial stage of poisoning for dynamic observation. In 71 cases (65.7%), there were ST-T changes, which were mainly abnormal T wave, inverted, bimodal, flat top and low flat and Q-Tc prolongation. 27 cases (25%) of ECC diagnosed “myocardial damage”. There was a linear correlation between abnormal changes of ECG and urinary arsenic levels in the same period (r = 0.617, P <0.01). T wave changes have no regional characteristics. ECG diagnosis of hypokalemia in 13 cases. Myocardial damage and coexistence of only 4 cases, with the same period of serum potassium test results basically consistent, but with the same period of urine arsenic content determination results were not significant. Tips promptly and comprehensively mark ECC and dynamic observation can provide an important reference for the rescue and treatment of acute arsenic poisoning.