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已知,广西肝癌高发病率与黄曲霉素对食物的污染有关,高发区居民的细胞免疫功能普遍低下.为了探讨黄曲霉毒素对细胞免疫功能的影响,作者用豚鼠作实验,观察动物在黄曲霉素中毒过程中,肝脏病变和细胞免疫水平的变化.免疫指标选用血中淋巴细细胞E花环活性(Ea)和总数(Et)的检测,以及DNCB和PHA的皮肤迟发超敏反应.
It is known that the high incidence of liver cancer in Guangxi is related to the contamination of aflatoxin to food, and the cellular immunity of residents living in high-incidence areas is generally low. To investigate the effect of aflatoxin on cellular immune function, the authors used guinea pigs as an experiment to observe animals in the During the process of aflatoxin poisoning, changes in hepatic pathological changes and cellular immunity were observed. The immune parameters used were the detection of erythrocytic E activity (Ea) and total number (Et) in blood lymphocytes, and delayed skin hypersensitivity of DNCB and PHA. .