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目的观察辛伐他汀联合奥扎格雷钠治疗不稳定型心绞痛(UA)的疗效。方法将136例UA患者随机分为观察组和对照组,各68例。对照组在常规处理基础上予奥扎格雷钠60mg加入生理盐水250ml中静脉滴注;观察组除对照组治疗药物外,予睡前口服辛伐他汀10mg,1次/d;两组疗程均为14d。结果观察组总有效率为85.29%,明显优于对照组的67.65%(p<0.05)。结论银杏达莫注射液与阿司匹林联合治疗不稳定性心绞痛疗效显著。辛伐他汀联合奥扎格雷钠能更好地改善UA患者血流动力学、血脂状况,降低血小板活化状态,改善微循环,联合用药安全、可靠,值得基层推广。
Objective To observe the efficacy of simvastatin combined with ozagrel sodium in the treatment of unstable angina pectoris (UA). Methods 136 patients with UA were randomly divided into observation group and control group, 68 cases in each. The control group was given intravenous drip of ozagrel 60mg into 250ml normal saline on the basis of routine treatment. The observation group was given simvastatin 10mg once daily before going to bed except the control group, 14d. Results The total effective rate in observation group was 85.29%, which was significantly better than that in control group (67.65%, p <0.05). Conclusion Ginkgo biloba injection combined with aspirin in the treatment of unstable angina pectoris has a significant effect. Simvastatin combined with ozagrel sodium can better improve hemodynamics and blood lipids in UA patients, reduce platelet activation status and improve microcirculation, and the combination therapy is safe and reliable, which is worth promoting at the grassroots level.