肝门胆管癌为最严重而常见的肝外胆管癌,占肝外胆管癌50%～75%。病理学特征多为分化较好的硬化性胆管癌或高分化腺癌。肿瘤生长缓慢,转移较晚,沿胆管粘膜下向胆管近侧或远侧端浸润生长,主要向肝内胆管侵犯,并经过胆管周围淋巴向肝内转移和直接侵犯肝门区肝实质、尾状叶肝实质和肝门区重要血管门静脉干及肝动脉等。手术切除困难,根治切除率更低,远期疗效差。目前国内肝门胆管癌 Hilar cholangiocarcinoma is the most common extrahepatic bile duct carcinoma, accounting for 50% to 75% of extrahepatic cholangiocarcinoma. The pathological features are mostly well-differentiated sclerosing or well-differentiated adenocarcinomas. The tumor grows slowly and metastasizes later. It infiltrates along the bile duct submucosal to the proximal or distal end of the bile duct. It is mainly invaded by the intrahepatic bile ducts and metastasizes to the liver through the peribiliary lymph and directly invades the hepatic parenchymal hepatic parenchyma. Liver parenchyma and hepatic portal veins, portal veins, and hepatic artery. Surgical removal is difficult, radical resection rate is lower, and long-term efficacy is poor. Current domestic hilar cholangiocarcinoma