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生物反应器是生物人工肝的核心部分,借助反应器,生物材料肝细胞与流经反应器的血液相互作用,可对肝衰竭患者进行辅助支持与治疗[1]。为构建理想的体外生物人工肝支持系统,我们用乳猪肝细胞和中空纤维管组成生物反应器,用药物转化试验对其性能进行了初步评价。1资料与方法1
Bioreactor is a core part of bioartificial liver. With the help of reactor, biomaterial liver cell and the blood flowing through the reactor, it can support and treat patients with liver failure [1]. In order to construct an ideal bioartificial liver support system in vitro, we used a bioreactor composed of suckling pig liver cells and hollow fiber tubes to evaluate its performance with drug conversion test. 1 Materials and Methods 1