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洋地黄类制剂是治疗小儿心脏疾病尤其是心力衰竭的主要药物。由于其治疗剂量与中毒剂量十分接近,极易发生毒性反应。因此,儿科医务工作者必须正确掌握洋地黄类药物的使用方法,既能达到治疗的目的,又不致于引起严重的毒性反应。今就有关问题介绍于下: 一、洋地黄的作用 (一)正性肌力作用:洋地黄的主要药理作用是增强心肌收缩力即正性肌力作用。用洋地黄治疗心力衰竭时所引起的心率减慢,心搏出量增加,已扩大的心脏缩小及升高的静脉压
Digitalis preparations for the treatment of heart disease in children, especially the main drug of heart failure. Because of its therapeutic dose and poisoning dose is very close, prone to toxic reactions. Therefore, pediatric medical workers must correctly understand the use of digitalis drugs, both to achieve the purpose of treatment, but not cause serious toxicity. Now on the issue described in the following: First, the role of digitalis (a) positive inotropic effect: the main pharmacological effects of digitalis is to enhance myocardial contractility that is positive inotropic effect. With digitalis treatment of heart failure caused by heart rate slowed, cardiac output increased, enlarged heart has decreased and elevated venous pressure