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目的:评价微波凝固术治疗鼻咽癌肺转移的临床价值。方法:回顾性分析2004年5月至2012年7月对98例鼻咽癌肺转移瘤患者168个病灶行微波凝固治疗的临床疗效,经微波凝固治疗1个月后行胸部CT增强扫描评价肿瘤治疗效果。结果:98例患者的168个病灶在治疗1月行CT复查评价疗效,完全缓解50个,部分缓解44个,稳定44个,进展30个,有效率达82.1%。全部病例术后均未出现严重并发症。患者1年、2年、3年的总生存率分别为46.7%,28.3%,13.4%。患者转移灶最大直径大小及累计转移灶的多寡对患者生存有显著影响。结论:微波凝固有较好的长、短期疗效,而且安全可靠,副作用小,是治疗鼻咽癌肺转移的有效方法之一。肺转移灶肿瘤最大径、累计转移灶的多寡均直接影响患者的总生存。
Objective: To evaluate the clinical value of microwave coagulation in the treatment of lung metastasis of nasopharyngeal carcinoma. Methods: The clinical curative effect of microwave coagulation therapy on 168 lesions of nasopharyngeal carcinoma patients with lung metastases from May 2004 to July 2012 was retrospectively analyzed. Thoracic CT scanning was performed to evaluate the tumor after 1 month of microwave coagulation therapy treatment effect. Results: A total of 168 lesions of 98 patients were evaluated by CT in January. The complete remission was 50, the partial remission was 44, the stability was 44, the progression was 30, the effective rate was 82.1%. No serious complications occurred in all cases after operation. Patients 1 year, 2 years, 3-year overall survival rates were 46.7%, 28.3%, 13.4%. The maximum size of metastases in patients and the cumulative number of metastases have a significant impact on patient survival. Conclusion: Microwave coagulation has a good long-term and short-term curative effect, and is safe and reliable with small side effects. It is an effective method for the treatment of pulmonary metastasis of nasopharyngeal carcinoma. The maximum diameter of lung metastases, the cumulative number of metastases directly affect the overall survival of patients.