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我们自1992年11月～1993年5月采用环丙沙星静脉滴注治疗肺部急性感染38例,取得了满意的疗效。现将结果报告如下。 1 资料与方法 1.1 病例选择均为首次单独应用该药的住院病人。根据症状、体征及临床资料符合肺部急性感染,并经其它两种以上抗生素治疗4天以上无效者。38例中,男25例,女13例。年龄19～83岁(平均63.2±13.6岁),其中60岁以上31例。病种包括慢性支气管炎、阻塞性肺气肿并发急性感染25例,其中合并肺心病心衰17例,合并肺性脑病4例;肺炎12例,其中合并休克2例,合并一氧化碳中毒1例;支气管扩张并感染1例。 1.2 病原菌 38例均采用洗涤法进行痰培养,其中阳性28例(73.7％),分别为假单孢菌5株,金黄色葡萄球菌3株,肺炎克雷白杆菌5株,绿脓杆菌4株,奇形变形杆菌1株,
From November 1992 to May 1993, we used ciprofloxacin intravenous infusion of 38 cases of acute pulmonary infection, and achieved satisfactory results. The results reported below. 1 Materials and Methods 1.1 Case Selection for the first time the single application of the drug inpatients. According to the symptoms, signs and clinical data in line with acute pulmonary infection, and by the other two or more antibiotics for more than 4 days were ineffective. 38 cases, 25 males and 13 females. Ages 19 to 83 years (average 63.2 ± 13.6 years), of which 31 cases over the age of 60. The disease includes chronic bronchitis, obstructive pulmonary emphysema complicated by acute infection in 25 cases, of which 17 cases of heart failure associated with pulmonary heart disease, pulmonary encephalopathy in 4 cases; pneumonia in 12 cases, including shock in 2 cases, combined with carbon monoxide poisoning in 1 case; Bronchiectasis and infection in 1 case. 1.2 Pathogenic bacteria 38 cases were washed with sputum culture, of which 28 cases were positive (73.7%), respectively Pseudomonas 5 strains, Staphylococcus aureus 3 strains, Klebsiella pneumoniae 5 strains, 4 strains of Pseudomonas aeruginosa , 1 strain of Proteus mirabilis,