论文部分内容阅读
目的:分析宁波市2006年以来疑似药品不良反应导致的死亡情况,为临床药品不良反应监测及合理用药提供参考。方法:采用回顾性分类统计,对收集到的26例死亡病例有关数据进行统计、分析。结果:死亡病例多发生于老年人,抗感染药物比例高,静脉给药发生率高,24例存在合并用药,累及的系统器官以全身性损害最多见。结论:慎用注射剂,加强临床ADR监测,加强药品使用管理,提高药品生产工艺和标准,加强药品商品名和说明书管理。
OBJECTIVE: To analyze the death caused by suspected adverse drug reactions in Ningbo since 2006, and provide a reference for monitoring adverse drug reactions and rational drug use. Methods: According to the retrospective classification statistics, the data of 26 death cases collected were statistically analyzed. Results: Most of the deaths occurred in the elderly. The proportion of anti-infectives was high and the incidence of intravenous administration was high. There were 24 cases with combined medication. The systemic organs involved were the most common. Conclusions: With caution injections, strengthen clinical ADR monitoring, strengthen the management of drug use, improve drug production technology and standards, and strengthen drug product name and instruction manual management.