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目的 观察生脉注射液治疗顽固性心力衰竭的临床疗效。方法 对 70例顽固性心力衰竭在原有用药的基础上 ,加用生脉注射液 4 0mL/d静脉滴注 ,连续使用 12d为 1个疗程 ,对心率、血压、呼吸、肺部音、腹围、尿量、下肢水肿和血BUN ,K+ ,Na+ 及氧耗量做治疗前后临床指标对比 ,并随机抽出 2 0例心功能在Ⅲ～Ⅳ的患者做血浆NO浓度治疗前后对比。结果 生脉注射液治疗后心肌收缩力明显加强 ,心搏出量、尿量增加 ,血压升高 ,血浆NO浓度降低。结论 生脉注射液是治疗顽固性心力衰竭较理想的中药制剂
Objective To observe the clinical effect of Shengmai Injection in treating refractory heart failure. Methods 70 cases of refractory heart failure on the basis of the original medication, plus Shengmai injection 40mL / d intravenous infusion, continuous use of 12d for a course of heart rate, blood pressure, breathing, lung sound, abdominal Circumference, urine volume, lower extremity edema and blood BUN, K +, Na + and oxygen consumption before and after treatment to do clinical indicators comparison, and randomly selected 20 patients with cardiac function in patients with Ⅲ ~ Ⅳ plasma NO concentration before and after treatment comparison. Results Shengmai injection significantly enhanced myocardial contractility, cardiac output, increased urine output, elevated blood pressure, plasma concentrations of NO decreased. Conclusions Shengmai Injection is an ideal traditional Chinese medicine for the treatment of refractory heart failure