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［目的］探索侵犯骨性胸壁的原发性肺癌（LCBJ）的外科治疗效果和手术方式。[方法]总结25例LCBI病例的外科治疗经验。[结果]全组1、3、5年生存率分别为56％、44％、39％，而N_0、N_1、N_2三级病人的1、3、5年生存率依秩递减10％－20％，N_0与N-2组生存率有统计学意义（P＝0．04）；死亡均发生在2年内，死因为远处转移；并发症发生率为12％，主要为呼吸道并发症。[结论]对LCBI病例可行肺胸壁enbloc切除，骨性胸壁缺损面积超过6cm×6cm应行胞壁重建。局部切除的彻底世、淋巴结转移情况及综合治疗的合理选择均可影响预后。
[Objective] To explore the surgical treatment effects and surgical methods of primary lung cancer (LCBJ) invading the thoracic wall. [Methods] Surgical treatment experience of 25 cases of LCBI was summarized. [Results] The overall 1-, 3-, and 5-year survival rates were 56%, 44%, and 39%, respectively, and the 1-, 3-, and 5-year survival rates of N_0, N_1, and N_2 tertiary patients decreased by 10% to 20%. The survival rate of N_0 and N-2 groups was statistically significant (P=0.04); death occurred within 2 years and death was due to distant metastasis; the incidence of complications was 12%, mainly respiratory complications. [Conclusion] The feasibility of resection of lung chest wall enbloc was feasible in LCBI cases, and the reconstruction of cell wall should be performed when the area of bone wall defects exceeds 6 cm x 6 cm. Thoracic local excision, lymph node metastasis, and rational choice of comprehensive treatment can affect prognosis.