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本文报道一株抗人血小板膜糖蛋白Ⅱb的单克隆抗体SZ-22。亲和层析法和免疫沉淀研究显示该抗体所识别的抗原位于血小板膜糖蛋白Ⅱb/Ⅲa复合物上;转移电泳证实SZ-22抗体与正常人血小板膜糖蛋白Ⅱb起反应,而与血小板无力症患者血小板无反应。放射免疫
This article reports a monoclonal anti-human platelet glycoprotein Ⅱ b antibody SZ-22. Affinity chromatography and immunoprecipitation studies showed that the antigen recognized by the antibody was located on the platelet glycoprotein IIb / IIIa complex. The transfer electrophoresis confirmed that the SZ-22 antibody reacted with normal platelet glycoprotein IIb, but not with platelet Patients with platelet no response. Radioimmunoassay