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目的全面分析和研究化脓性脑膜炎儿童病患在治疗前后脑脊液检查结果的变化分析。方法分别检测45例化脓性脑膜炎儿童病患在治疗之前和治疗之后脑脊液中细胞数量、总蛋白数量、葡萄糖水平的变化情况,观察儿童病患在治疗过程中的临床疗效。结果所有儿童病患中,治愈31例(68.9%),好转11例(24.4%),无效2例(4.4%),死亡1例(2.2%)。在治疗后期脑脊液细胞计数、压力与治疗之前进行比较有显著的降低,在研究对象中恢复正常的儿童病患分别为34例(75.6%)和53例(88%)。在治疗后期总蛋白数量、葡萄糖水平和氯化物水平与治疗之前进行比较有显著的改善。结论抗生素药物的使用及相关治疗可有效改善:化脑儿童病患的脑脊液细胞数量、压力水平、总蛋白水平、葡萄糖及氯化物水平。
Objective To comprehensively analyze and study the changes of cerebrospinal fluid (CSF) examination results in children with purulent meningitis before and after treatment. Methods The changes of cell number, total protein and glucose in cerebrospinal fluid of 45 children with purulent meningitis were detected before and after treatment, and the clinical effect of children in treatment was observed. Results Of all children, 31 (68.9%) were cured, 11 (24.4%) were improved, 2 (4.4%) were ineffective and 1 (2.2%) died. Cerebrospinal fluid cell counts and stress were significantly reduced at the end of treatment compared with before treatment, with 34 (75.6%) and 53 (88%) children returning to normal in the study, respectively. There was a significant improvement in total protein amount, glucose level, and chloride level after treatment compared with before treatment. Conclusion The use of antibiotics and related therapies can effectively improve cerebrospinal fluid (CSF) cell number, stress level, total protein level, glucose and chloride levels in children with brain disorders.